Archives of Current Research International

This cross-sectional study investigated the relationships between well-being, stress, burnout, depression, and anxiety at the University of Cape Coast. A sample of 279 students completed a validated self-report measures assessing well-being, perceived stress, burnout, depression, and anxiety using a comprehensive scale. Well-being was evaluated using a comprehensive well-being scale, while stress, burnout, depression, and anxiety were assessed using standardised instruments. Bivariate correlation and multiple regression analyses were conducted to explore the relationships between the variables. The results indicated significant negative correlations between well-being, stress, burnout, depression and, anxiety. Higher levels of stress, burnout, depression, and anxiety were associated with lower levels of well-being among University of Cape Coast students. The findings of this study highlight the considerable impact of stress, burnout, depression, and anxiety on the well-being of University of Cape Coast students. These results underscore the importance of addressing these factors to support students' mental health and overall well-being. Targeted interventions focused on stress management, burnout prevention, and mental health support may be crucial in promoting a positive and thriving university experience for students.  This study contributes to the growing literature on student mental health in Ghanaian higher education and highlights the need for institutional policies promoting holistic well-being.