Heat Stress, Antioxidant Supplementation and HSP70 mRNA Expression in Growing Pigs

Arindam Chakraborty

Krishi Vigyan Kendra, Lakhimpur, Assam Agricultural University, India.

Soumen Naskar

ICAR, Indian Institute of Agricultural Biotechnology (ICAR-IIAB), India.

Simson Soren *

Lakhimpur College of Veterinary Science, Assam Agricultural University, India.

Sanjib Borah

Lakhimpur College of Veterinary Science, Assam Agricultural University, India.

Donna Phangchopi

Lakhimpur College of Veterinary Science, Assam Agricultural University, India.

Snigdha Hazarika

Lakhimpur College of Veterinary Science, Assam Agricultural University, India.

Biju Borah

Lakhimpur College of Veterinary Science, Assam Agricultural University, India.

Sayed Nabil Abedin

SRF, ICAR RC for NEH Region, Umiam, Meghalaya. India.

Shiney George

College of Veterinary Science, AAU, Khanapara, Guwahati, India.

*Author to whom correspondence should be addressed.


Abstract

Heat stress poses significant challenges to livestock productivity, particularly in pigs, due to their limited thermoregulatory mechanisms. This study aimed to evaluate the seasonal effects of heat stress on growth performance, haematological and hormonal level, as well as the relative mRNA expression of HSP70 in growing pigs supplemented with melatonin and vitamin E. Results showed that haematological parameters, serum cortisol, lactate dehydrogenase, and average body weight were adversely affected during the summer season. While antioxidant supplementation did not significantly influence haematological profiles or LDH levels, it reduced cortisol levels during summer. Vitamin E supplementation resulted in a significant decrease in HSP70 mRNA expression during summer, indicating improved oxidative stability. Seasonal variations notably affect pigs' growth and health, with vitamin E supplementation reducing HSP70 expression during summer, highlighting the challenges of tropical climates.

Keywords: Heat stress, growing pigs, antioxidants supplementation, HSP70 expression


How to Cite

Arindam Chakraborty, Soumen Naskar, Simson Soren, Sanjib Borah, Donna Phangchopi, Snigdha Hazarika, Biju Borah, Sayed Nabil Abedin, and Shiney George. 2025. “Heat Stress, Antioxidant Supplementation and HSP70 MRNA Expression in Growing Pigs”. Archives of Current Research International 25 (9):152–163. https://doi.org/10.9734/acri/2025/v25i91484.