Comparative Evaluation of Two Therapeutic Protocols in Canine Babesiosis
Vikram Singh Gurjar *
Department of Veterinary Medicine, Post-Graduate Institute of Veterinary Education and Research, Rajasthan University of Veterinary and Animal Sciences, (Jobner), Jaipur-302031, Rajasthan, India.
Rashmi Singh
Department of Veterinary Medicine, Post-Graduate Institute of Veterinary Education and Research, Rajasthan University of Veterinary and Animal Sciences, (Jobner), Jaipur-302031, Rajasthan, India.
Dhram Singh Meena
Department of Veterinary Medicine, Post-Graduate Institute of Veterinary Education and Research, Rajasthan University of Veterinary and Animal Sciences, (Jobner), Jaipur-302031, Rajasthan, India.
Nirmal Kumar Jeph
Department of Veterinary Medicine, Post-Graduate Institute of Veterinary Education and Research, Rajasthan University of Veterinary and Animal Sciences, (Jobner), Jaipur-302031, Rajasthan, India.
Saksham Mandawat
Department of Veterinary Medicine, Post-Graduate Institute of Veterinary Education and Research, Rajasthan University of Veterinary and Animal Sciences, (Jobner), Jaipur-302031, Rajasthan, India.
*Author to whom correspondence should be addressed.
Abstract
This study evaluated the efficacy of clindamycin hydrochloride and diminazene aceturate in treating canine babesiosis. A total of 12 canines diagnosed with babesiosis were included for the study which was presented to the Government Veterinary Polyclinic and Department of Veterinary Medicine, PGIVER, Jaipur (Rajasthan) India. The diagnosis was based on their history of tick infestation, distinctive clinical characteristics, hemato-biochemical tests and the blood smear staining technique (Giemsa staining). The dogs were categorized into two groups as group 1 and 2 on the basis of therapeutic protocol. Group 1 and 2 dogs were treated with Diminazine aceturate @ 7mg/kg BW and orally Clindamycin @25mg/kg BW twice daily respectively. On blood smear examination for babesiosis, group 1 demonstrated 100% recovery on day 7, but group 2 shown 33.3% recovery on day 7. In group 1, all hemato-biochemical values returned to normalcy on day 10 of therapy, however in group 2 normal parameters were seen on day 15 of treatment.
Keywords: Canine Babesiosis, clindamycin hydrochloride, Diminazene aceturate, therapeutics