Spatial Analysis of Seroconversion for Chagas Disease in Donors from a Public Blood Bank in the State of Pará
Brenda Laryssa Lima Gonçalves
*
Evandro Chagas Institute, Brazil.
Rosane do Socorro Pompeu de Loiola
Institute of Biological Sciences – UFPA, Brazil.
Daniela Cristiane da Cruz Rocha
Evandro Chagas Institute, Brazil.
*Author to whom correspondence should be addressed.
Abstract
Background: Mortality linked to Chagas disease is higher than other parasitic diseases. It is estimated that 10,000 deaths per year are related to it, and more than 25 million people are exposed to the risk of contracting the infection. Between 2016 and 2020, 1200 cases of the pathology were reported in Pará. Despite ongoing surveillance, gaps remain in understanding the spatial heterogeneity of seroconversion patterns among blood donors in the Brazilian Amazon, particularly in highly endemic states such as Pará.
Aims: identify the profile and spatial aspect of seroconversion for Chagas disease in donors from a blood bank in the state of Pará from 2016 to 2022.
Methodology: A study was carried by quantitative, ecological and descriptive research with a cartographic approach by the analysis of the municipalities that are part of the blood networks from Hemotherapy and Hematology Foundation of Pará (HEMOPA). Spatial analysis was performed using QGIS 3.32.3, applying incidence rates standardized by population and classifying municipalities into risk categories based on the mean and standard deviation thresholds.
Results: The results revealed that during the period, the number of donors throughout the state of Pará had a prevalence of 0.02%, totaling 170 cases. Most of these cases occurred in the capital, Belém, where the main blood center is located. The data revealed a predominance of seroconversion in men (74.12%). The age of these donors ranged from 21 to 71 years with a mean of 43.28± 11.55 years. Incidence rates among regional centers ranged from 0.392 to 2.259 per 100,000 donors, with hotspots identified especially in Capanema, Abaetetuba, Altamira and Redenção.
Conclusion: The use of geoprocessing is essential for analyzing the distribution of cases between municipalities, guiding public policies and investments in hemotherapy.
Keywords: Chagas disease, Trypanosoma cruzi, seroconversion, Pará